Option A
EBOO
Extracorporeal blood oxygenation and ozonation: a continuous-flow treatment that filters, oxygenates, and ozonates a large volume of blood over about 60 to 90 minutes.
The Full Service PageBoth EBOO and major autohemotherapy treat the blood with ozone, but they are not the same procedure. EBOO runs a continuous flow of blood through a filter, oxygenating and ozonating a much larger volume over a longer session. Major autohemotherapy treats a smaller fixed volume in cycles. The names are often blurred, so it is worth knowing the difference before you book.
Option A
Extracorporeal blood oxygenation and ozonation: a continuous-flow treatment that filters, oxygenates, and ozonates a large volume of blood over about 60 to 90 minutes.
The Full Service PageOption B
A fixed volume of blood, often a few hundred milliliters, is drawn, mixed with ozone, and reinfused, sometimes across several passes.

Side by Side
| Attribute | EBOO | Ozone Therapy (Major Autohemotherapy) |
|---|---|---|
| Blood Volume Treated | Large, continuous flow | Smaller, a fixed volume per pass |
| Session Length | About 60 to 90 minutes | About 30 to 60 minutes |
| Filtration Step | Yes, blood passes through a filter | No filtration step |
| Protocol Intensity | The more intensive of the two | A lighter, more widely available protocol |
| Typical Use | Advanced inflammatory, autoimmune, and optimization protocols | General immune and circulatory support |
| Availability in Nashville | Rare; offered at very few clinics | More widely available at functional-medicine clinics |
| Supervision | Licensed medical supervision | Clinician-administered |
Which to Pick
Pick EBOO
Choose EBOO if you specifically want the more intensive, continuous-flow procedure, usually for advanced inflammatory, autoimmune, or optimization goals, delivered under medical supervision.
Pick Ozone Therapy (Major Autohemotherapy)
Choose major autohemotherapy if you want a lighter, more widely available ozone protocol for general immune and circulatory support.
Do Both
Many people start with lighter ozone or foundational IV support and move up to EBOO only if a goal justifies the more intensive protocol.
Common Questions
In a sense. Both expose your blood to ozone, but EBOO treats a much larger volume through continuous filtration, which is why it is considered the more advanced and intensive of the two. Major autohemotherapy is a lighter, more widely available protocol.
It depends on your goal and how aggressive you want to be. People targeting stubborn inflammatory or autoimmune patterns, or running advanced optimization, often seek out EBOO. For general immune or circulatory support, autohemotherapy is a reasonable and more accessible option.
Ozone therapy is not broadly approved by the FDA for most uses, and that is true of both. It makes measured expectations and proper clinical screening especially important. Discuss it with your own physician if you manage a chronic condition.
True EBOO is rare locally. Next Health Nashville offers it in the city; most other clinics in the area offer ozone by major autohemotherapy rather than EBOO.